PAHs-induced metabolic aberrations and intact circadian rhythms in zebrafish: a promising approach for aquatic surveillance.

ABSTRACT: Polycyclic aromatic hydrocarbons (PAHs), recognized as teratogenic and carcinogenic pollutants, exhibit moderate-to-high acute toxicity and long-term detrimental effects on aquatic organisms. However, conventional monitoring methods often fail to detect early-stage sublethal impacts of PAHs, potentially due to limited disruption of intrinsic circadian rhythms during initial exposure periods. To investigate the physiological responses of aquatic species to PAHs, we employed real-time biomonitoring to evaluate metabolic alterations in juvenile zebrafish (Danio rerio), including oxygen consumption rate (OR), carbon dioxide excretion rate (CR), ammonia-nitrogen excretion rate (AE), respiratory quotient (RQ), and ammonia quotient (AQ), alongside their circadian rhythmicity under PAH exposure. T

SUBMITTER: Chen M 

PROVIDER: S-EPMC12365042 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature