Dynamic cerebral autoregulation during and 3 months after endovascular treatment in large vessel occlusion stroke.

ABSTRACT: Acute ischemic stroke caused by large vessel occlusion is effectively treated by endovascular treatment (EVT). However, treatment could be further refined by improved understanding of the pathophysiology, including dynamic cerebral autoregulation (dCA). Near-infrared spectroscopy (NIRS) requires virtually no setup time and enables dCA investigation during EVT by measuring dynamic concentration in cortical oxygenated hemoglobin (OxyHb). We aimed to investigate dCA during EVT, before and after recanalization, and at follow-up (FU) after 24 h and 90 days. We applied interhemispheric transfer function analysis (TFA) of low-frequency (LF) oscillations (0.07-0.2 Hz) in OxyHb that yields the dCA measures, gain and phase shift. LF phase shift increased immediately after recanalization for patients

SUBMITTER: Heiberg AV 

PROVIDER: S-EPMC12365094 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature