Biogenic synthesis of silver nanoparticles using Sida cuneifolia leaf extract for enhanced antibacterial, cytotoxic, and anti-biofilm activities.

ABSTRACT: Antimicrobial resistance (AMR) is one of the global threats that needs to be addressed. Nanotechnology represents a promising way to address this issue due to its multifaceted mode of action. This study aimed to synthesize and evaluate the antimicrobial and anti-biofilm properties of silver nanoparticles using S. cuneifolia leaves extract. The formation and properties of AgNPs were characterized using a UV-Vis spectrophotometer, an FT-IR spectrophotometer, TEM, and XRD. Disc diffusion and MIC were used to evaluate the antibacterial activity of AgNPs towards E. coli, S. flexneri, and S. aureus. The antibacterial action of silver NPs was observed using SEM, and cytotoxicity was assessed using the hemolysis assay. The anti-biofilm was evaluated against E. coli and S. aureus. From the results

SUBMITTER: Ismael M 

PROVIDER: S-EPMC12365124 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature