Log odds of positive lymph nodes as a prognostic marker in resectable triple negative breast cancer.

ABSTRACT: This study aimed to assess the prognostic value of the log odds of positive lymph nodes (LODDS) in resectable nonmetastatic triple-negative breast cancer (TNBC) and its potential role in informing postoperative treatment decisions. A retrospective cohort study was conducted using data from the SEER 17 registries, including patients aged 20-79 diagnosed with TNBC. The association between LODDS and cancer-specific survival (CSS) was analyzed using the restrictive cubic splines (RCS) method. Propensity score matching (PSM) and survival analysis were employed to evaluate the effect of LODDS on treatment outcomes. Between 2010 and 2021, breast-conserving surgery (BCS) emerged as the predominant surgical approach for resectable nonmetastatic TNBC, with its proportion increasing from 49.3 to 52.1

SUBMITTER: Zheng C 

PROVIDER: S-EPMC12365269 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature