Xuebijing alleviates high-voltage electrical burn-induced acute kidney injury by inhibiting neutrophils and inflammation.

ABSTRACT: This study aimed to investigate the clinical effect of Xuebijing in alleviating acute kidney injury (AKI) after high-voltage electrical burns by inhibiting neutrophils, inflammatory cells, and its potential influence on reactive oxygen species (ROS). Ninety-six patients with AKI following high-voltage electrical burns, admitted to our hospital from February 2023 to December 2024, were included. They were randomized using a computer-generated random number sequence into two groups: a study group (Xuebijing, n = 48) and a control group (n = 48). This study was conducted in an open-label manner. Neutrophil, inflammatory cell, and ROS levels, as well as kidney function and oxidative stress factors (SOD, MDA), were compared at baseline (1 h before treatment) and 7 days post-treatment. Adverse r

SUBMITTER: He X 

PROVIDER: S-EPMC12365283 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature