Physical fitness and clinically assessed disease burden in long-term childhood cancer survivors-The SURfit study.

ABSTRACT:

Background

Identifying disease burden among childhood cancer survivors (CCS) can guide tailored care. Physical fitness predicts health and mortality and may help reduce disease burden in CCS. This study aimed to 1) describe the burden of clinically ascertained adverse health outcomes in long-term CCS, and 2) investigate the association between physical fitness and adverse health outcomes.

Methods

This study used baseline data of the SURfit study, a randomized controlled physical activity trial. The authors included 163 CCS, diagnosed <16 years, ≥16 years at enrollment, and ≥5 years since last cancer diagnosis. Clinically assessed health outcomes were categorized using the Common Terminology Criteria for Adverse Events. Physical fitness was assessed by cardiopulmonary-exercis

SUBMITTER: Mayr AK 

PROVIDER: S-EPMC12365372 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature