Development of a Deprescribing Intervention for Proton Pump Inhibitors in Primary Care: A Co-Design Approach With General Practitioners and Patients.

ABSTRACT: Proton Pump Inhibitors (PPIs) are widely prescribed medications globally. PPIs are often inappropriately used - for example, prescribed without a clear indication, at higher-than-necessary doses, or for longer durations than needed - resulting in increased risks of adverse health outcomes such as nutrient deficiencies, osteoporosis-related fractures, and kidney disease. The effectiveness of current deprescribing interventions is inconsistent; this may relate to the misalignment with behavioural mechanisms, supporting the need for a mechanism-driven approach that targets key behavioural determinants. We co-designed a PPI deprescribing intervention with patients and health professionals for the Swiss primary care setting. This involved identifying behavioural determinants of PPI deprescribin

SUBMITTER: Weir KR 

PROVIDER: S-EPMC12365437 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature