Comparison of Disease Progression From Prostate Cancer Diagnosis to Metastatic or Nonmetastatic Castrate-Resistant Prostate Cancer (CRPC) Patients: CaPA Study.

ABSTRACT:

Background

Prostate cancer (PC) patients resistant to castration have decreased survival. Analysis of patient characteristics and disease management can contribute to new strategies to prevent or delay progression to castrate-resistant prostate cancer (CRPC). This study aimed to characterize and compare PC patients from initial PC diagnosis to metastatic CRPC (mCRPC) versus nonmetastatic (nmCRPC) stages in a real-world setting in Portugal.

Methods

A multicenter, retrospective, non-interventional study was conducted across 18 Portuguese sites. Consenting adult patients (age ≥ 18 years) diagnosed with CRPC, either metastatic or nonmetastatic, were included in the study at the time of diagnosis or within 12 months of CRPC diagnosis.

Results

Between November 2020 and Dece

SUBMITTER: Costa P 

PROVIDER: S-EPMC12365608 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature