Global Burden and Gender Disparities in Head and Neck Cancers Among Adults Aged 40-64, 1990-2021: A Systematic Analysis From the Global Burden of Disease Study 2021.

ABSTRACT: Head and neck cancer (HNC) is a significant global health concern, with incidence rising after the age of 40. This study aims to analyze the trends in prevalence, incidence, mortality, and disability-adjusted life years (DALYs), focusing on regional and gender differences. This research utilized data from the Global Burden of Disease (GBD) 2021 study. Key metrics such as the age-standardized prevalence rate (ASPR), age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and age-standardized disability-adjusted life years rate (ASDR) were analyzed. These metrics were used to examine trends from 1990 to 2021, focusing on gender and regional differences, and projections were made using the Nordpred method to predict future disease burdens up to 2045. The analysis cover

SUBMITTER: Luo Z 

PROVIDER: S-EPMC12365661 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature