Leveraging infant visit PrEP screening INtegration & tasK shifting to improve post-partum HIV prevention in Malawi (LINK): a cluster-randomized trial evaluation of a postpartum HIV prevention package among breastfeeding women in Malawi.

ABSTRACT:

Background

Elimination of vertical transmission of HIV remains a major global public health priority. In Malawi, more than one-third of pediatric HIV acquisitions are attributed to perinatal HIV acquisition during breastfeeding. HIV pre-exposure prophylaxis (PrEP) is a crucial biomedical tool to keep women free of HIV and eliminate vertical transmission, but effectiveness has been hampered by poor uptake and premature discontinuation. Implementation science approaches are needed to improve uptake, persistence, and adherence to PrEP among postpartum women at risk of HIV.

Methods

LINK is a type I hybrid effectiveness implementation cluster-randomized trial conducted at 12 service delivery sites within Lilongwe district, Malawi. The LINK model is a novel postpartum HIV preventi

SUBMITTER: Rutstein SE 

PROVIDER: S-EPMC12366187 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature