Haptoglobin as a supplement in in vitro embryo culture: a tool for improving bovine embryo development and quality.

ABSTRACT:

Background

Recent studies have indicated the potential involvement of haptoglobin in a variety of events during mammalian reproduction, with previous research highlighting its efficacy in promoting porcine embryo development. The present study aims to provide a comprehensive investigation of haptoglobin expression and secretion in the bovine uterus, with a view to assessing its impact on bovine in vitro embryo production. A systematic study was conducted on cows in different oestrous stages, early follicular, late follicular, early luteal and late luteal stages. Relative haptoglobin mRNA abundance was quantified by RT-qPCR, and the expression of the protein was analysed by immunohistochemistry. The results were complemented by proteomic analyses of the uterine fluid. In vitro bovin

SUBMITTER: Canon-Beltran K 

PROVIDER: S-EPMC12366215 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature