Clinical outcomes of gastroenteropancreatic neuroendocrine neoplasms in Taiwan: A multicenter registry study-TCOG T1214 study.

ABSTRACT:

Background

Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) account for more than 50% of all NENs. The survival of patients with GEP-NENs has improved based on early diagnosis and improved treatment strategies. The real-world data of GEP-NENs in Taiwan are limited. A multicenter registry study was conducted to obtain real-world data on GEP-NENs in Taiwan.

Methods

Patients with pathologically diagnosed GEP-NENs were enrolled. Data were on the baseline characteristics, treatment strategies, and patient survival. Also evaluated was the expression status of six biomarkers, including SSTR2, SSTR5, PDX-1, CDX-2, mASH1, and NeuroD, in tumors. Overall survival (OS) was analyzed and plotted via the Kaplan-Meier method. Cox regression analysis was used to analyze the prognos

SUBMITTER: Tsai HJ 

PROVIDER: S-EPMC12366283 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature