Deciphering the phenol degradation metabolic pathway in <i>Scedosporium apiospermum</i> HDO1.

ABSTRACT: The filamentous fungus Scedosporium apiospermum is a microorganism capable of phenol degradation. Phenol is a petroleum-derived pollutant and a compound widely used in several industries. As a result of its widespread use, phenol is commonly discarded and accumulated in soils and water bodies. In this study, overexpressed and repressed genes that produce enzymes involved in phenol metabolism were identified in S. apiospermum HDO1 when the fungus grows in the presence of phenol. The fungus was grown with either glucose (control) or phenol as the sole carbon source to achieve this. RNA from the mycelium was extracted and sequenced using the Illumina Hiseq-4000 platform, with paired-end libraries. Eighteen genes coding for enzymes related to catechol ortho-cleavage, catechol met

SUBMITTER: Diaz Ortiz LL 

PROVIDER: S-EPMC12366324 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature