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Association between gastrointestinal disorders and sleep-related problems: the mediating effect of depression.


ABSTRACT:

SUBMITTER: Ye S 

PROVIDER: S-EPMC12366357 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature

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Association between gastrointestinal disorders and sleep-related problems: the mediating effect of depression.

Ye Shicheng S   Sui Lili L   Zeng Xuan X   Dong Zhiwei Z   Liao Zhongqin Z   Qu Chongzheng C  

BMC gastroenterology 20250819 1


BACKGROUND: The relationship between gastrointestinal(GI) diseases and sleep-related problems—such as sleep trouble and sleep disorders—remains insufficiently understood. METHODS: Data were derived from the 2005–2014 U.S. National Health and Nutrition Examination Survey (NHANES). Multicollinearity was evaluated using variance inflation factors. Multivariable logistic regression and subgroup analyses were conducted to assess the association between GI diseases and sleep trouble. Mediation analyse  ...[more]

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