Bacterial isolates and antibiotic resistance in critically ill sepsis patients at a tertiary hospital in Ethiopia.

ABSTRACT:

Background

Sepsis is a pressing global public health issue, particularly among patients admitted to intensive care unit (ICU), and it is linked to a high incidence of morbidity and mortality. Current understanding of bacterial profiles, antibiotic resistance patterns, and the magnitude of Extended-Spectrum Beta-Lactamase (ESBL) and Carbapenemase (CP) producing isolates in critically ill patients is vital for implementing strong management approaches tailored to combat antibiotic resistance and improve patient outcomes.

Methods

A prospective cross-sectional study was carried out involving 149 patients admitted to ICU with a presumptive diagnosis of sepsis at Jimma University Medical Center (JUMC) from October 2023 to October 2024. A structured questionnaire was administered t

SUBMITTER: Kiya GT 

PROVIDER: S-EPMC12366403 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature