Association between the atherogenic index of plasma and risk of large-artery atherosclerotic ischemic stroke.

ABSTRACT: Ischemic stroke caused by large artery atherosclerosis (LAA) is a major subtype of ischemic stroke and poses a heavy public health burden. Plasma atherogenic index (AIP) reflects the balance between pro- and anti-atherogenic lipid components and has emerged as a potential biomarker of cardiovascular disease. The aim of this study was to investigate the role of AIP in predicting ischemic stroke caused by LAA. This retrospective, cross-sectional study involved 2,382 ischemic stroke patients. AIP values were measured, and subjects were further stratified according to AIP levels. Univariate and multivariate logistic regression analyses were conducted to explore the relationship between AIP and the risk of LAA. Restricted cubic spline (RCS) analysis was used to detect the potential non-linear r

SUBMITTER: Zhong W 

PROVIDER: S-EPMC12366434 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature