Molecular Epidemiology and Genetic Diversity of Orientia tsutsugamushi From Patients and Small Mammals in Xiangyun County, Yunnan Province, China.

ABSTRACT: Scrub typhus, also known as Tsutsugamushi disease (TD), is an acute febrile illness that poses a significant public health threat to nearly one billion people in the Asia-Pacific region. The disease is caused by Orientia tsutsugamushi (OT) and is primarily transmitted through the bite of chigger mite larvae. Due to its nonspecific clinical manifestations, early diagnosis is challenging, often leading to misdiagnosis or untreated cases. Yunnan Province, located on China's border, reports the highest annual incidence of scrub typhus, highlighting the need to better understand OT infection in both human patients and small mammals in this region. In this study, clinical data on scrub typhus cases in Xiangyun County People's Hospital were retrospectively collected. Nested polymerase chain react

SUBMITTER: Chen L 

PROVIDER: S-EPMC12366444 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature