Effects of high-intensity exercise on rehabilitation of patients after stroke: a systematic review and meta-analysis of randomized controlled trials with high quality.

ABSTRACT: To present the latest systematic review and meta-analysis of high-quality randomized controlled trials (RCTs) comparing high-intensity exercise with routine rehabilitation in stroke patients. PubMed, Web of Science, and Cochrane were used to searching literature up to October 2024. RCTs with sample size of ≥50 individuals were included. Primary outcomes assessed were the Six-Minute Walking Test (6MWT), Ten-Meter Walk Test (10MWT), VO2peak, Berg Balance Scale (BBS), Timed Up and Go test (TUG), and Montreal Cognitive Assessment (MoCA). Standardized mean differences (SMD) with 95% confidence intervals (CI) were used for pooling data. Stability was evaluated by sensitivity analysis. Seven RCTs with 724 participants were included. Meta-analysis revealed significant improvements in the 6MWT (SMD

SUBMITTER: Li S 

PROVIDER: S-EPMC12366500 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature