Brain network dynamics associated with intentional weight loss in older adults.

ABSTRACT: Current obesity research suggests a link between obesity and challenges in executive functions such as decision-making, inhibitory control, and reward valuation, but what separates older individuals who are vulnerable to these deficiencies from those who are resilient remains unknown. We have mounting evidence that suggests disruptions in brain networks are a key factor. However, most of the brain connectivity analyses performed in the obesity literature estimate a static, unchanging brain network for each experimental scanning session. In this paper, we conduct a state-based dynamic functional connectivity analysis on functional magnetic resonance imaging (fMRI) data collected during a food-cue task from 58 older adults with obesity. Our intent was to build upon an original investigation

SUBMITTER: Shappell HM 

PROVIDER: S-EPMC12366634 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature