Predictive value and ranking of writhing and fidgety movements for cerebral palsy: A meta-analysis based on the Superiority Index.

ABSTRACT:

Background

This meta-analysis assessed the diagnostic value of writhing and fidgety general movements (GMs) for predicting cerebral palsy.

Methods

We searched PubMed, EMBASE, Cochrane Library, CINAHL, and Web of Science for cohort or case-control studies evaluating GMs. We calculated the superiority index (S), sensitivity, specificity, likelihood ratios, diagnostic odds ratio (DOR), and area under the curve (AUC) using STATA.

Results

Eight studies were included. For writhing movements, S = 1, sensitivity = 0.99, specificity = 0.69, AUC = 0.91, and DOR = 166. For fidgety movements, S = 3, sensitivity = 0.95, specificity = 0.87, AUC = 0.97, and DOR = 144. Subgroup analyses by study design, risk population, and sample size consistently showed better predictive performanc

SUBMITTER: Wang T 

PROVIDER: S-EPMC12366895 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature