A comprehensive guide to conduct a systematic review and meta-analysis in medical research.

ABSTRACT: Systematic reviews and meta-analyses are essential tools in medical research. Systematic reviews are a type of literature review that uses a systematic process to identify and assess all available literature on a specific research question. A meta-analysis is a statistical method of synthesizing the results of a systematic review by quantitatively combining data. The process begins with formulating a well-defined research question using frameworks. Comprehensive literature searches across multiple databases, including PubMed, Embase, and Cochrane, to ensure the inclusion of diverse studies. Tools like EndNote and Covidence streamline reference management and study selection, enhancing efficiency and accuracy. Quality assessment using tools like the Cochrane Risk of Bias Tool and Newcastle-

SUBMITTER: Calderon Martinez E 

PROVIDER: S-EPMC12366998 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature