DAPT Is Comparable to OAC Following LAAC With WATCHMAN FLX: A National Registry Analysis.

ABSTRACT:

Background

Left atrial appendage occlusion (LAAO) is an approved alternative for stroke prevention in atrial fibrillation for patients with an "appropriate rationale" to avoid long-term oral anticoagulation (OAC). Many patients undergoing LAAO are at high risk of bleeding.

Objectives

This study sought to investigate whether dual antiplatelet therapy (DAPT) is a safe alternative to OAC (direct oral anticoagulation [DOAC] or warfarin) with aspirin after LAAO.

Methods

Using National Cardiovascular Data Registry LAAO registry data, patients undergoing Watchman FLX (Boston Scientific) implantation (August 5, 2020-September 30, 2021) were included in 1:1 propensity-matched analyses comparing discharge medication regimens (DAPT, DOAC/aspirin, or warfarin/aspirin). A composit

SUBMITTER: Coylewright M 

PROVIDER: S-EPMC12367332 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature