Clinical associations of worsening physical function as measured by HAQ-DI scores in systemic sclerosis.

ABSTRACT:

Background

Functional disability is a major concern for individuals with systemic sclerosis (SSc). The Health Assessment Questionnaire-Disability Index (HAQ-DI) measures the ability to perform activities of daily living, with higher scores indicating poorer function.

Objective

To define the frequency and clinical associations of minimum clinically important difference (MCID) change in HAQ-DI scores in SSc.

Methods

Australian Scleroderma Cohort Study participants with two or more HAQ-DI scores ⩽ 2 visits apart were included. Generalised estimating equations were used to model the correlates of the MCID improvement (-0.125 points) and MCID worsening (+0.14 points) of HAQ-DI scores. Subgroup analysis in those with incident (⩽5 years SSc duration at recruitment) and diffu

SUBMITTER: Fairley JL 

PROVIDER: S-EPMC12367724 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature