The clinical impact of 16S ribosomal RNA PCR and sequencing in the identification of bacterial infections: a 7-year report from a Lebanese tertiary care center.

ABSTRACT: The identification of bacterial pathogens in the clinical setting is essential for providing optimal care and improving outcomes. The primary objective of this study was to assess the performance of the 16S test in bacterial identification from different samples and determine its impact on clinical outcomes. This was a retrospective study of patient samples collected from all age-groups at the American University of Beirut Medical Center (AUBMC), from May 2016 to December 2022. Descriptive statistics were conducted to calculate the 16S test positivity rate and to describe the different types of organisms. Univariate analyses were performed to study the clinical impact of the 16S test and its comparison to the conventional bacterial culture among different characteristics. A p ≤ 0.05 was co

SUBMITTER: Youssef N 

PROVIDER: S-EPMC12367777 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature