Effect of slice thickness on quantitative analysis of interstitial lung disease: a retrospective volumetric chest CT study.

ABSTRACT:

Introduction

High-resolution computed tomography (HRCT) is essential for evaluating interstitial lung disease (ILD). The effect of slice thickness on threshold-based quantification of individual ILD components remains underexplored. This study investigates the effect of slice thickness on ILD quantification using Lung CT Analyzer.

Methods

Retrospective analysis of 53 ILD patients (mean age 64.3 ± 14.1 years) who underwent chest CT scans with HRCT (slice thickness ≤ 1.25 mm) and conventional CT (CCT, ≥ 2.5 mm) reconstructions. Quantitative lung volumes, functional parenchyma, emphysema, ground-glass opacity (GGO), consolidation and affected parenchyma were assessed. The effects of contrast media (CM) application and ILD pattern was assessed separately.

Results

Emphysem

SUBMITTER: Puseljic M 

PROVIDER: S-EPMC12367816 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature