Low-dose ultrahigh-resolution PCCT enhances subsolid nodule characterization.

ABSTRACT:

Purpose

To characterize invasion-associated CT features in pulmonary subsolid nodules using low-dose ultrahigh-resolution (UHR) photon-counting CT (PCCT) images and evaluate UHR's diagnostic superiority over standard high-resolution (HR) images.

Methods

Patients with subsolid lung adenocarcinoma were recruited for chest scan on PCCT to obtain UHR and standard HR images between November 2023 and May 2024. Nodule characteristics were visually assessed and histogram features were extracted from each nodule. Image quality and radiation dose at previous energy-integrating detector CT (EID-CT) of 30 patients were compared with those of PCCT. Differences between UHR and standard HR, PCCT and EID-CT were compared using paired McNemar-test or paired Wilcox-test.

Results

One hu

SUBMITTER: Yan Q 

PROVIDER: S-EPMC12367857 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature