Mitochondrial proteomic adaptations to daily torpor in the Djungarian hamster (Phodopus sungorus).

ABSTRACT: Hibernation is an adaptive strategy that conserves energy in response to environmental challenges. While mitochondrial proteomic adaptations are well-documented in deep hibernators, the proteomic changes underlying daily torpor remain less clear. We investigated mitochondrial proteomic adaptations in the liver of a daily hibernator, the Djungarian hamster (Phodopus sungorus), across different hibernation phases. Hamsters were maintained under long-day (summer) or short-day photoperiods (winter), to induce torpor. Livers from summer, torpor, and interbout euthermia phases were analyzed by liquid chromatography-mass spectrometry with labelled standards of mitochondrial energy metabolism proteins, resulting in accurate quantitative proteomics. Differential protein regulation was assessed usin

SUBMITTER: Kovacs A 

PROVIDER: S-EPMC12367877 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature