A novel rapid rule-out protocol for acute chest pain using H-FABP point-of-care testing.

ABSTRACT: Emergency department (ED) visits have gradually increased throughout recent years, contributing to the widespread problem of ED overcrowding. The purpose of this study was to develop a rapid rule-out strategy for patients with acute chest pain that integrates clinical characteristics and Heart-type fatty acid binding protein (H-FABP) to improve ED patient care. H-FABP point-of-care test results of 130 patients were integrated into a modified HEART score, with a score ≤ 3 points indicating rule-out of acute coronary syndrome (ACS). Diagnostic performance was assessed with comparative analyses between the Ex-ACS protocol, the conventional HEART score, and the European Society of Cardiology (ESC) 0/1-h algorithm. In this study cohort, eight patients (6.2%) were diagnosed with NSTEMI and none

SUBMITTER: Demirel O 

PROVIDER: S-EPMC12368026 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature