Global burden of cancer attributable to HIV: a worldwide incidence analysis.

ABSTRACT: People living with HIV are at increased risk of multiple infection-related cancers due to HIV-driven immunosuppression. However, the global burden of cancer attributable to HIV remains unestimated. We aimed to comprehensively estimate the global and regional cancer burden attributable to HIV in 2022, and to understand geographical disparities in this burden. Nine cancer types considered causally linked to HIV infection were assessed in this worldwide incidence analysis: Kaposi sarcoma; non-Hodgkin lymphoma; Hodgkin lymphoma; and cervical, anal, penile, vulvar, vaginal, and conjunctival cancer. Cancer-specific population attributable fractions (PAFs) were calculated, primarily from meta-analyses reporting relative risks and HIV prevalence estimates sourced from UNAIDS 2023. PAFs were applie

SUBMITTER: Huang Y 

PROVIDER: S-EPMC12368413 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature