Intersecting Risk Factors Associated With High Syphilis Seroprevalence Among a Street-Involved Population in Canada.

ABSTRACT: Syphilis has reemerged as a global public health concern. In Ontario, Canada's most populous province, a 340% increase in infectious syphilis cases was observed between 2013 and 2023. This surge was accompanied by a demographic shift, with women emerging as the fastest-growing at-risk group. We examined intersecting risk factors associated with syphilis seropositivity among a street-involved population. Data were collected from the Syphilis Point of Care Rapid Test and Immediate Treatment Evaluation (SPRITE) study-an outreach model of care implemented by 8 public health units (PHUs) across Ontario between 2023 and 2024. Reactive treponemal antibodies defined syphilis seroprevalence. A mixed-effects regression with a log-binomial distribution was used to evaluate the association between ris

SUBMITTER: Mackrell L 

PROVIDER: S-EPMC12368418 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature