A Contrast-Agnostic Method for Ultra-High Resolution Claustrum Segmentation.

ABSTRACT: The claustrum is a band-like gray matter structure located between putamen and insula whose exact functions are still actively researched. Its sheet-like structure makes it barely visible in in vivo magnetic resonance imaging (MRI) scans at typical resolutions, and neuroimaging tools for its study, including methods for automatic segmentation, are currently very limited. In this paper, we propose a contrast- and resolution-agnostic method for claustrum segmentation at ultra-high resolution (0.35 mm isotropic); the method is based on the SynthSeg segmentation framework, which leverages the use of synthetic training intensity images to achieve excellent generalization. In particular, SynthSeg requires only label maps to be trained, since corresponding intensity images are synthesized on the

SUBMITTER: Mauri C 

PROVIDER: S-EPMC12368599 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature