Synthesis of Dendritic Oligo-Glycerol Amphiphiles with Different Hydrophobic Segments to Improve their Performance as Nanocarriers.

ABSTRACT: A new class of non-ionic dendritic amphiphiles has been developed from biobased chemicals, in particular glycerol-based dendrons coupled to commercially available acids via the Steglich esterification process. These non-ionic amphiphiles are functionalized with different hydrophobic segments to investigate the contribution of the same towards their guest transport behaviour. Therefore, different alkyl chains i.e, C8 and C12, as well as two different aromatic units were introduced as a hydrophobic segments and G1-oligo-glycerol as a hydrophilic segment. Their physicochemical properties were characterized by different techniques such as dynamic light scattering and fluorescence measurements. The results show that these amphiphiles form a very uniform micellar supramolecular structures that i

SUBMITTER: Kumari P 

PROVIDER: S-EPMC12368886 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature