Systematic evidence mapping informs a class-based approach to assessing personal care products and pubertal timing.

ABSTRACT:

Background

Personal care products (PCPs) contain many different compounds and are a source of exposure to endocrine disrupting chemicals (EDCs), including phthalates and phenols. Early-life exposure to EDCs commonly found in PCPs has been linked to earlier onset of puberty.

Objective

To characterize the human and animal evidence on the association between puberty-related outcomes and exposure to PCPs and their chemical constituents and, if there is sufficient evidence, identify groups of chemicals and outcomes to support a systematic review for a class-based hazard or risk assessment.

Methods

We followed the OHAT systematic review framework to characterize the human and animal evidence on the association between puberty-related health outcomes and exposure to PCPs and

SUBMITTER: Taylor KW 

PROVIDER: S-EPMC12368981 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature