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Nanostructured Microsphere Production by Osmotic Extraction of Microfluidic Emulsion Templates.


ABSTRACT: Microscale emulsion droplets are versatile soft templates for assembling nanoparticle powders and forming secondary microparticles. When combined with microfluidics, nanostructured microparticles can be produced with precise size and uniformity. However, assembly requires removal of the droplet solvent, which is particularly slow for water-in-oil emulsions. This has been a longstanding challenge, preventing the deployment of emulsion-structured nanomaterials at scale. Here, an osmotic pressure-driven method is presented that achieves controlled water extraction from emulsion droplets. This is a faster, more cost-effective, and sustainable alternative to prolonged heating; particle solidification is achieved by introducing a second emulsion containing a high solute concentration. The effect

SUBMITTER: Sanders KA 

PROVIDER: S-EPMC12368995 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature