Determination of lymph node metastasis using quantitative ultrasound elastography of papillary thyroid carcinoma nodule: a systematic review and meta-analysis.

ABSTRACT: papillary thyroid carcinoma (PTC) as the most common thyroid tumor, tends to invade adjacent organs, especially lymphatic system. This study aimed to evaluate the discrimination performance of ultrasound elastography (USE) in assessing PTC nodule for determination of cervical lymph node metastasis (CLNM). The protocol was pre-registered at ( https://osf.io/r5tc8 ). Using PubMed, Web of Science, Embase, and Cochrane Library, studies published up to March 10, 2025, were identified. Data extraction was conducted independently, and a random-effects bivariate model was applied to estimate pooled differentiation accuracy estimates. Twenty-one studies were included involving 7559 patients; 2790 (36%) were positive for CLNM, while 4769 (63%) were negative. The pooled Emean values for positive and

SUBMITTER: Mohebbi A 

PROVIDER: S-EPMC12369039 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature