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Efficacy and safety of programmed death-1 inhibitors combined with chemotherapy in patients with advanced gastric cancer.


ABSTRACT:

SUBMITTER: Cheng X 

PROVIDER: S-EPMC12369166 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature

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Efficacy and safety of programmed death-1 inhibitors combined with chemotherapy in patients with advanced gastric cancer.

Cheng Xiaofei X   Zhang Yang Y   Li Xingyuan X   Xu Zhenning Z   Chen Yaolin Y  

BMC gastroenterology 20250821 1


OBJECTIVE: Programmed death-1 (PD-1) inhibitors combined with chemotherapy show certain clinical benefits in advanced gastric cancer patients, but more evidence is still needed. The present study aimed to investigate the efficacy and safety of PD-1 inhibitors combined with chemotherapy in these patients. METHODS: Forty-three patients with advanced gastric cancer receiving PD-1 inhibitors (including camrelizumab, sintilimab, and tislelizumab, 200 mg every 3 weeks) combined with chemotherapy were  ...[more]

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