Comparative transcriptome analysis of pectoralis major muscles affected by white striping, wooden breast and spaghetti meat in male and female broiler chickens.

ABSTRACT:

Background

Growth-related myopathies, including white striping (WS), wooden breast (WB), and spaghetti meat (SM), compromise broiler meat quality, causing significant economic losses. Although these myopathies share some histological features, their molecular mechanisms remain incompletely understood, particularly regarding sex-specific differences. This study aimed to compare transcriptomic profiles of normal and defective pectoralis major muscles to identify biological pathways underlying male and female myopathies. Transcriptomic analysis was performed on RNA-seq data from pectoralis major muscles of male and female Ross 308 broilers. Then, differentially expressed genes (DEGs) and enriched pathways were identified using edgeR and functional annotation tools.

Results

SM s

SUBMITTER: Boskovic Cabrol M 

PROVIDER: S-EPMC12369168 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature