Characterization of <i>Photobacterium damselae</i> subsp. <i>damselae</i> isolated from a spotted seal (<i>Phoca largha</i>) (Pinnipedia: Phocidae) stranded in Korea.

ABSTRACT:

Introduction

Photobacterium damselae subsp. damselae (PDD) is an emerging marine bacterial pathogen that infects marine animals and humans, causing fatal necrotizing fasciitis and histamine fish poisoning. Despite its clinical and ecological importance, the microbiological and genomic characteristics of PDD remain largely unknown.

Methods

We report the first case of systemic infection caused by PDD in a free-ranging spotted seal (Phoca largha) stranded in Korea. Histopathological and microbial examinations were performed, followed by genomic analysis of the isolated PDD strain GCUPdd. Histamine production capability and cytotoxic effects on human cells were also evaluated.

Results

PDD was identified as the presumptive cause of systemic infection i

SUBMITTER: Cha TS 

PROVIDER: S-EPMC12369411 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature