Longitudinal Clustering of Psychopathology Across Childhood and Adolescence: An Approach Toward Developmentally Based Classification.

ABSTRACT: Current classification systems of psychopathology focus on cross-sectional symptomatology rather than continuity, discontinuity and comorbidity across development. Here, a community sample of 600 youth was assessed every 3 years from early childhood through late adolescence using semi-structured diagnostic interviews. We used longitudinal k-means clustering of joint-diagnostic trajectories to identify 6 distinct clusters (healthy, childhood anxiety, childhood/adolescent ADHD, adolescent depression/anxiety, adolescent depression/substance use, and early childhood disruptive behavior). When comparing psychopathology clusters to the healthy cluster on age 3 predictors (parental education and psychopathology, early environment, temperament, cognitive and social functioning) and age 18 f

SUBMITTER: Lawhead C 

PROVIDER: S-EPMC12369591 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature