Relationship between heart rate variability parameters and inflammatory activity in patients with Crohn's disease: a retrospective study.

ABSTRACT: It is widely recognized that individuals with Crohn's disease (CD) often experience impaired autonomic nervous system (ANS) function. However, the specific relationship between autonomic activity and inflammatory processes in CD remains uncertain. The objective of this study was to investigate the association between autonomic nervous function, as assessed through heart rate variability (HRV) parameters, and the Crohn's disease activity index (CDAI). This cross-sectional study involved 82 CD patients. Demographic and medical history data were gathered, and disease activity was evaluated using the CDAI. Short-term HRV measurements were obtained from all participants. Various adjustments to the model and trend analysis indicate that the HRV parameters are significantly negatively correlated

SUBMITTER: Wang B 

PROVIDER: S-EPMC12369601 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature