Impact of paternal hepatitis B on pregnancy outcomes in couples undergoing assisted reproductive technology treatment: a systematic review and meta-analysis.

ABSTRACT: This study intends to evaluate the influence of hepatitis B virus (HBV) infection on clinical pregnancy rate (CPR) and live birth rate (LBR) per woman and cycle in couples who achieved pregnancy through assisted reproductive technology (ART). PubMed, Embase, CNKI, Scopus, Web of Science, and Wangfang databases were comprehensively searched for articles reporting data on pregnancies achieved through ATR and providing information on the paternal HBV status and CPR and LBR. A random-effects model was used for the meta-analyses to pool odds ratios (OR) with corresponding confidence intervals (CI). Subgroup analyses were done based on the matching status. The analysis included 10 studies (4,848 participants) for CPR per woman, 10 studies (28,951 participants) for CPR per cycle, four studies (2,

SUBMITTER: Gao J 

PROVIDER: S-EPMC12369629 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature