Ex vivo liquid core fiber photometry with high-resolution 3D printing.

ABSTRACT: High resolution 3D printing emerges as an alternative to microfabrication due to its fine resolution along with one-step manufacturing. Thus, it is broadly used in many fields, such as biological and chemical applications. We introduce such a technique to the design of the optofluidic probe by integrating optics and microfluidics as an ex vivo liquid core fiber photometry. We build the optofluidic probes with various T-shapes and conduct the transmission measurements and the ray tracing simulations, where the results are comparable. Through the transmission and fluorescence measurements, we obtain optimized curl T-shape dimensions of 524 μm wide, ~50 μm thick, and 350 μm long with longitudinal spaces between them of 260 um. Furthermore, a heightened level of complexity in structure, charac

SUBMITTER: Chang Y 

PROVIDER: S-EPMC12369891 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature