Invasive candidiasis following lung transplant: An Assessment of impact utilizing a national insurance claims cohort.

ABSTRACT: Lung transplant recipients (LTRs) are susceptible to invasive candidiasis (IC). This study aimed to assess the incidence, risk factors, and impact of IC on mortality in LTRs using a national insurance claims cohort. We conducted a retrospective cohort study using administrative claims data from the OptumLabs® Data Warehouse. We identified LTRs from January 1, 2005, to December 31, 2023, using procedural codes. Exclusion criteria included re-transplantations and pre-transplant IC. We employed multivariable logistic regression to identify risk factors for IC and Cox Proportional Hazard models to assess the impact of IC on mortality. Among 1279 LTRs, 131 (10.2%) developed IC, primarily during the initial hospitalization for lung transplantation (index hospitalization). The median time to IC d

SUBMITTER: Pennington KM 

PROVIDER: S-EPMC12370120 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature