Comprehensive analysis of the role of deep inspiration breath-hold in right-sided breast cancer radiotherapy: A focus on cardiac substructures and right coronary artery.

ABSTRACT: The deep inspiration breath-hold (DIBH) technique, a method used to minimize radiation exposure to normal tissues in breast cancer patients, has primarily been applied to patients with left breast cancer. However, this study, with its unique focus on right breast cancer, aims to evaluate the potential benefits of DIBH on the right coronary artery (RCA), cardiac substructures, and liver dose in right breast cancer radiotherapy. Forty right-sided breast cancer patients were included in this study. Radiotherapy planning using 3D, IMRT, and VMAT was performed using both free-breathing (FB) and DIBH techniques. Two treatment plans were generated per patient, and organ-at-risk (OAR) doses were compared using the Wilcoxon signed-rank test. Patients were analyzed based on regional nodal irradiatio

SUBMITTER: Semiz V 

PROVIDER: S-EPMC12370404 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature