The mitigative effects of <i>Blautia producta</i> 1009924 on DSS-induced intestinal inflammation.

ABSTRACT:

Introduction

The gut microbiota plays a crucial role in the treatment of inflammatory bowel disease (IBD). Recent studies have shown that the abundance of Blautia producta is associated with host inflammatory bowel disease (IBD), yet its specific mechanism of action remains to be further investigated.

Methods

The strain Blautia producta 1009924 (B. producta 1009924) was isolated from fresh fecal samples, and its biological characteristics and genomic features were analyzed. In this study, a zebrafish intestinal inflammation model was established by induction with 0.5% dextran sulfate sodium (DSS) for 72 h to evaluate the effect of B. producta 1009924 on alleviating intestinal inflammation.

Results

This strain B. producta 1009924 is a

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12370734 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature