Selective Plasticity of Hippocampal Sub-Regions in the Amnestic Mild Cognitive Impairment After Acupuncture.

ABSTRACT: Acupuncture has been demonstrated to be effective in reducing cognitive decline in patients with amnestic mild cognitive impairment (aMCI). Hippocampal atrophy has been typically reported as a core neuromechanism in the aMCI. However, whether and how hippocampal subregions plasticity exists in aMCI after acupuncture remains largely unknown. We aimed to explore gray matter alterations in the hippocampal subregions of aMCI after acupuncture. A randomized, controlled, blind research was conducted. A cohort of 53 patients with aMCI was randomly assigned to either the verum acupuncture (VA) group or the sham acupuncture (SA) group. Each group received 24 treatment sessions (three times per week for 8 weeks). Clinical evaluation and magnetic resonance imaging scans were performed at baseline and

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12370839 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature