Axillary Hyperpigmentation Treatment: A Systematic Review of the Literature.

ABSTRACT: Post-inflammatory hyperpigmentation is a common dermatologic complaint that affects different parts of the body. Axillary hyperpigmentation (AH) is a common dermatologic complaint, with no standard treatment. We aim to address the efficacy and safety of the studied treatment modalities for AH. A systematic search was done using "axillary" and "hyperpigmentation"-related keywords/MeSH terms through PubMed/Medline, Scopus, Web of Science, and Embase. Ten studies on AH were categorized into topical treatments, light/laser-based therapies, and comparative approaches. Topical agents like niacinamide, desonide, sweet orange extract, Perilla frutescens leaf extract, Cyperus rotundus oil, glycolic acid, and novel serums demonstrated varying degrees of pigmentation reduction, with desonide and C. r

SUBMITTER: Vahabi SM 

PROVIDER: S-EPMC12371607 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature