The effect of pomegranate products on glycemic profile in adults: a GRADE- assessed systematic review and dose-response meta-analysis of randomized controlled trials.

ABSTRACT: Pomegranate consumption may have a beneficial effect on glucose control and insulin resistance due to its bioactive compounds. However, the results of available clinical trials are inconsistent. To address these inconsistencies, we conducted a meta-analysis of 34 randomized clinical trials (RCTs) evaluating the effects of pomegranate on glycemic parameters in adults. A thorough search was conducted across multiple databases until December 2024 to identify trials that investigated the impact of pomegranate on glucose control and insulin sensitivity. We calculated the effect size, reported as the weighted mean difference (WMD) with 95% confidence intervals (CIs), based on the net changes in fasting blood glucose (FBS), insulin, HOMA-IR, and Hemoglobin A1c (HbA1c). Among the 407 records, this

SUBMITTER: Mohammadzaheri F 

PROVIDER: S-EPMC12372205 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature