Dataset Information
GeneSetCluster 2.0: a comprehensive toolset for summarizing and integrating gene-sets analysis.
Ontology highlight
ABSTRACT:
SUBMITTER: Ortega-Legarreta A
PROVIDER: S-EPMC12372222 | biostudies-literature | 2025 Aug
REPOSITORIES: biostudies-literature
Publications
GeneSetCluster 2.0: a comprehensive toolset for summarizing and integrating gene-sets analysis.
BMC bioinformatics 20250821 1
BACKGROUND: Gene-Set Analysis (GSA) is commonly used to analyze high-throughput experiments. However, GSA cannot readily disentangle clusters or pathways due to redundancies in upstream knowledge bases, which hinders comprehensive exploration and interpretation of biological findings. To address this challenge, we developed GeneSetCluster, an R package designed to summarize and integrate GSA results. Over time, we and users as well identified limitations in the original version, such as difficul ...[more]