Dataset Information
Development and validation of a multimodal model integrating gut microbiota and metabolite for identifying sarcopenia in patients with MASLD: a study from two centers in China.
Ontology highlight
ABSTRACT:
SUBMITTER: Wan S
PROVIDER: S-EPMC12372311 | biostudies-literature | 2025 Aug
REPOSITORIES: biostudies-literature
Publications
Development and validation of a multimodal model integrating gut microbiota and metabolite for identifying sarcopenia in patients with MASLD: a study from two centers in China.
Nutrition journal 20250822 1
BACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common chronic liver disease worldwide, and identifying sarcopenia is critical since it is correlated with poor prognosis. Little is known about mechanistic alterations in the pathogenesis of this condition. This study aimed to explore the alterations in the gut microbiome and metabolome in patients with sarcopenia and develop a predictive model. METHODS: We performed shotgun metagenomic sequencing and unt ...[more]